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| 15 Feb 2024 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 172,723 | $399.66 | $69,030,474 15 Feb 2024 | 925,209 | ↗ |
| 2 Jan 2024 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 16,848 | $900.00 | $15,163,200 2 Jan 2024 | 180,000 | ↗ |
| 11 Dec 2023 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 25,155 | $848.42 | $21,342,005 11 Dec 2023 | 765,327 | ↗ |
| 23 Mar 2023 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 3,656 | $804.26 | $2,940,375 23 Mar 2023 | 196,848 | ↗ |
| 6 Feb 2023 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 13,189 | $800.08 | $10,552,255 6 Feb 2023 | 200,504 | ↗ |
| 22 Dec 2021 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 442,267 | $221.08 | $97,776,388 22 Dec 2021 | 1,169,835 | ↗ |
| 13 Aug 2021 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 50,000 | $625.29 | $31,264,500 13 Aug 2021 | 887,483 | ↗ |
| 5 Aug 2021 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 50,000 | $600.06 | $30,003,000 5 Aug 2021 | 937,483 | ↗ |
| 21 Jun 2021 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 80,000 | $538.90 | $43,112,000 21 Jun 2021 | 2,108 | ↗ |
| 30 Dec 2020 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 398,079 | $52.03 | $20,712,050 30 Dec 2020 | 908,303 | ↗ |
| 9 Mar 2020 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 246,736 | $30.63 | $7,557,524 9 Mar 2020 | 713,990 | ↗ |
| 24 Feb 2020 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 118,123 | $420.17 | $49,631,741 24 Feb 2020 | 517,799 | ↗ |
| 11 Dec 2019 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 245,295 | $21.25 | $5,212,519 11 Dec 2019 | 521,876 | ↗ |
| 13 Dec 2018 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 244,048 | $16.80 | $4,100,006 13 Dec 2018 | 167,185 | ↗ |
| 12 Dec 2017 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 195,438 | $21.92 | $4,284,001 12 Dec 2017 | 786,786 | ↗ |
| 15 Dec 2016 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 195,079 | $20.32 | $3,964,005 15 Dec 2016 | 697,000 | ↗ |
| 15 Dec 2016 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 195,079 | $20.32 | $3,964,005 15 Dec 2016 | 697,000 | ↗ |
| 16 Dec 2015 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 1,921 | $52.03 | $99,950 16 Dec 2015 | 501,921 | ↗ |
| 2 Dec 2015 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 43,348 | $549.03 | $23,799,352 2 Dec 2015 | 500,000 | ↗ |
| 30 Oct 2015 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 182,818 | $11.64 | $2,128,002 30 Oct 2015 | 682,818 | ↗ |
| 16 Dec 2014 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 3,264 | $30.63 | $99,976 16 Dec 2014 | 503,264 | ↗ |
| 27 Aug 2014 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 5,720 | $314.31 | $1,797,853 27 Aug 2014 | 505,720 | ↗ |
| 11 Feb 2014 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 189,463 | $9.49 | $1,798,004 11 Feb 2014 | 1,257,806 | ↗ |
| 19 Dec 2013 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 4,705 | $21.25 | $99,981 19 Dec 2013 | 1,068,343 | ↗ |
| 12 Dec 2013 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 9,599 | $260.44 | $2,499,964 12 Dec 2013 | 1,115,994 | ↗ |
| 6 May 2013 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 192,308 | $13.00 | $2,500,004 6 May 2013 | 1,309,638 | ↗ |
| 19 Dec 2012 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 50,846 | $13.77 | $700,149 19 Dec 2012 | 1,117,330 | ↗ |
| 14 Dec 2012 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 10,369 | $109.29 | $1,133,228 14 Dec 2012 | 1,304,811 | ↗ |
| 1 May 2012 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 33,165 | $134.83 | $4,471,637 1 May 2012 | 833,041 | ↗ |
| 26 Mar 2012 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 33,150 | $120.24 | $3,985,956 26 Mar 2012 | 866,206 | ↗ |
| 15 Feb 2012 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 133,332 | $8.50 | $1,133,322 15 Feb 2012 | 901,079 | ↗ |
| 5 Jan 2012 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 27,713 | $58.00 | $1,607,354 5 Jan 2012 | 833,041 | ↗ |
| 30 Nov 2011 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 200,000 | $28.01 | $5,602,000 30 Nov 2011 | 928,701 | ↗ |
| 3 Dec 2009 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 100,000 | $8.77 | $877,000 3 Dec 2009 | 688,235 | ↗ |
| 16 Dec 2008 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 100,000 | $7.41 | $741,000 16 Dec 2008 | 636,103 | ↗ |
| 13 Apr 2007 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 400 | $24.98 | $9,992 13 Apr 2007 | 67,096 | ↗ |
| 13 Apr 2007 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 90,444 | $10.56 | $955,089 13 Apr 2007 | 157,540 | ↗ |
| 9 Apr 2007 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 9,556 | $10.56 | $100,911 9 Apr 2007 | 67,196 | ↗ |
| 3 Jan 2007 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 30,000 | $9.50 | $285,000 3 Jan 2007 | 77,563 | ↗ |
| 9 Jan 2006 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 900 | $17.33 | $15,597 9 Jan 2006 | 65,926 | ↗ |
| 27 Dec 2005 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 25,000 | $12.75 | $318,750 27 Dec 2005 | 83,950 | ↗ |
| 9 Jan 2004 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 1,339 | $15.33 | $20,527 9 Jan 2004 | 63,478 | ↗ |
| 18 Sep 2003 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 26,211 | $20.75 | $543,878 18 Sep 2003 | 54,540 | ↗ |
| 17 Sep 2003 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Sale | 300 | $20.70 | $6,210 17 Sep 2003 | 80,751 | ↗ |
| 17 Sep 2003 | REGNRegeneron Pharmaceuticals, Inc. | George Yancopoulos Bd. Co-Chair, President, and CSO | Option | 126,310 | $4.24 | $535,554 17 Sep 2003 | 172,948 | ↗ |